#6732 EPICARDIAL ADIPOSE TISSUE AND REVERSE EPIDEMIOLOGY IN DIALYSIS PATIENTS

Abstract Background and Aims Conventional risk factors of cardiovascular disease mortality in the general population such as body mass is relate to adverse outcome dialysis patients, but often an opposite direction (reverse epidemiology). On contrary, epicardial adipose tissue (EAT) has reported have a local inflammatory proatherogenic effect. Thus, association EAT direct measures region specific chronic kidney (CKD) been studied. Method The study evaluated 37 CKD-5 patients hemodialysis (mean duration 26±30 months, 70% males, 57% African-American, 48% diabetic) that underwent MSCT measure coronary artery calcium (CAC) score. CAC distribution quartiles was assessed. Finally, we measured patients’ index (BMI) categorized them normal (BMI 18.5-25 kg/m2) abnormal BMI >25 kg/m2). Results mean 28.6±5.7 kg/m2, volume 66±29 ml 102±69 for groups. There correlation between vintage while showed inverse relationship with (p = 0.05). In this small sample size, only marginally significant 0.7). significantly correlated age 0.02), history 0.03) diabetes 0.001). Conclusion face appear support notion state inflammation malnutrition.